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Colgate Total ®
Extend your
professional care
NEW Colgate Total® Active Prevention System 15x more effective at fighting the root cause of many oral health problems* when used together7
Rapid
foaming
action
action
Proven
antibacterial
protection8
protection8
Instant and
long lasting
antibacterial
protection**
protection**
In partnership with dental professionals,
Colgate Total® is at the forefront of active prevention.
* Such as gingivitis and cavities by reducing bacteria buildup in 6 weeks starting in week 1, vs non-antibacterial fluoride toothpaste and flat-trim toothbrush.
** With twice daily rinsing.
† In 6 weeks starting in week 1, vs non-antibacterial fluoride toothpaste and flat-trim toothbrush, when used together.
Phosphates
complex Sn2+ ions
Stannous ions are generally
unstable and easily oxidized in
contact with air, water, and heat9
The NEW formulation of Colgate Total® was developed to enhance stability of stannous ions
Nitrate ions help block degradation of bioactive Sn2+
NEW Colgate Total® Active Prevention Plus Deep Clean Toothpaste
Breakthrough preventative
technology
Fights bacterial biofilm
3xreduction of
bacterial biofilm*10
Controls regrowth and makes biofilm less pathogenic8,1
Fights dental calculus
31%reduction in
dental calculus*11
Actively prevents tartar formation and buildup
Fights oral malodor
85% of participants
achieved fresh breath**12
Keeps breath fresher for 12 hours†
* Vs. non-antibacterial fluoride toothpaste with 3 months continued use.
** In a clinical study, 12 hours post-brushing with 3 weeks of continued use vs baseline.
† Vs. non-antibacterial fluoride toothpaste with 3 weeks twice daily use.
1 To help prevent plaque buildup.
2 With 2x daily brushing and 4 weeks continued use
Innovative technology*8,10-13
High levels of bioavailable stannous**
24-hour antibacterial protection†
Long-lasting efficacy†
Delightful brushing experience
Designed for high patient compliance‡
* Vs non-antibacterial fluoride toothpaste for reduction of plaque, gingivitis, tartar, malodor, and sensitivity.
** Soluble stannous measured via aqueous simple solutions of the ingredients after 2 weeks accelerated aging at 60°C.
† With 2x daily brushing and 4 weeks of continued use.
‡ Consumer Test (Home Use Test) – US, BZ, UK.
NEW Colgate Total® Active Prevention Mouthwash
Helps prevent:
Gingivitis
Plaque
Bad Breath
Kills 99.9% of bacteria†
* Protection against plaque and gingivitis germs when used after brushing.
** Clinically proven to help prevent gingivitis.
† Including bacteria that cause bad breath, and accumulate in plaque and cause gingivitis and/or gum disease, when measured in saliva immediately after use.
NEW Colgate Total® Active Prevention Toothbrush Rapid foaming action for deeper toothpaste delivery*
Specially engineered,
high density center pads to polish away stains and prevent plaque buildup
Small head
to clean hard-to-reach molars
Outer tapered bristles
gently clean harder-to-reach areas like gingival margins and interproximal and posterior areas
Floss-Tip® bristles**
that clean hard to reach areas most prone to dental problems**
5000+ soft, high density bristles designed with a contoured fi t for deeper* delivery of the toothpaste to problem prone areas
* Vs. an ordinary flat-trim toothbrush.
** This toothbrush does not replace flossing
Left uncontrolled, bacterial biofilm puts patients at risk1
It’s diffcult for even the most diligent of patients to control biofilm at home.2
Brushing alone reduces bacterial plaque by ONLY 42%*3
Not all toothpastes are equally effective in actively preventing oral health problems**4
Only 1 in 4 patients uses mouthwash regularly5
Often, patients don’t recognize their oral health problems until symptoms appear.
The good news: Patients want your advice.
Research shows the highest predictor of patient loyalty is a dental professional’s explanation of treatment options. 6
To offer more biofilm control,
get your patients started on a better daily system†
References: 1. Ledder RG, Lattimer J., Forbes S., et al. Visualization and Quantification of the Oral Hygiene Effects of Brushing, Dentifrice Use, and Brush Wear Using a Tooth Brushing Simulator. Front Public Health. 2019;7:9122. 2. Ray RR, Pattnaik S. Technological advancements for the management of oral biofilm. Biocatalysis Agricultural Biotechnol. 2024;56(6):103017. 3. Chapple IL, Van der Weidjen F., Doerfer C., et al. Primary prevention of periodontitis: managing gingivitis. J Clin Periodontol. 2015;42 Suppl 16:S71-6. 4. Clark-Perry D, Levin L. Comparison of new formulas of stannous fluoride toothpastes with other commercially available fluoridated toothpastes: A systematic review and meta-analysis of randomised controlled trials. Int Dent J. 2020;70(6):418-26. 5. McFarlane TV, Kawecki MM, Cunningham C, et al. Mouthwash use in general population: results from Adult Dental Health Survey in Grampian, Scotland. J Oral Maxillofac Res. 2011;1(4):e2. 6. El Dalatony, M. M., Alshareef, R. I., Alkahtani, A. R., Alhajri, S. M., Alhumaidany, T. M., AlQarni, W. A., ... & Aldossary, M. S. (2023). Patient satisfaction as a determinant of patient loyalty to the Dentist in Dental Clinics. Journal of Patient Experience, 10, 23743735231166506. 7. Ayad, F., Hetata, M., Ahmed, R., Okai, T., Govindaraju, G., Mateo, L.R., Ryan, M., & García-Godoy, B. Antiplaque and Antigingivitis Effects of a Novel Oral Care Regimen Featuring Stannous Fluoride Toothpaste, a Unique Toothbrush, and Cetylpyridinium Chloride Mouthwash: A Randomized Clinical Trial. J Evid Based Dent Pract. 2025;25(2):102123. https://doi.org/10.1016/j.jebdp.2025.102123. 8. Chakraborty B, Seriwatanachai D, Triratana T, et al. Antibacterial effects of a novel stannous fluoride toothpaste stabilized with nitrate and phosphates (SNaP): in vitro study and randomized controlled trial. Compend Contin Educ Dent. 2024;45 suppl 3:12-20. 9. Dorn RW, Carnahan S., Cheng CY., et al. Structural characterization of tin in toothpaste by dynamic nuclear polarization enhanced 119Sn solid-state NMR spectroscopy. Nat Commun. 2023;14:7423. 10. Lee S, Li Y, Mateo L, et al. A 6-month randomized controlled trial to measure the efficacy of a stannous fluoride toothpaste stabilized with nitrate and phosphates (SNaP) on dental plaque and gingivitis. Compend Contin Educ Dent. 2024;45 suppl 3:21-29. 11. Stellitano M, et al. Effect of a Stannous Fluoride Toothpaste on Supragingival Calculus Formation, submitted for 2025 AADOCR presentation. 12. Cabelly A, Bankova M, Darling J, et al. Stannous fluoride toothpaste stabilized with nitrate and phosphates (SNaP) reduces oral malodor: a randomized clinical study. Compend Contin Educ Dent. 2024;45 suppl 3:40-45. 13. Liu Y, Lavender S, Ayad F, et al. Effect of a stannous fluoride toothpaste stabilized with nitrate and phosphates (SNaP) on dentin hypersensitivity: in vitro study and randomized trial. Compend Contin Educ Dent. 2024;45 suppl 3:30-39.
